解决：未能加载文件或程序集“AjaxControlToolkit”或它的某一个依赖项。拒绝访问。

 

解决办法：

给这个文件夹“C:\WINDOWS\Microsoft.NET\Framework\v2.0.50727\Temporary ASP.NET Files” 设置了读写权限，如下图所示：

 

“/”应用程序中的服务器错误。

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未能加载文件或程序集“AjaxControlToolkit”或它的某一个依赖项。拒绝访问。

说明: 执行当前 Web 请求期间，出现未处理的异常。请检查堆栈跟踪信息，以了解有关该错误以及代码中导致错误的出处的详细信息。

异常详细信息: System.IO.FileLoadException: 未能加载文件或程序集“AjaxControlToolkit”或它的某一个依赖项。拒绝访问。

源错误:

执行当前 Web 请求期间生成了未处理的异常。可以使用下面的异常堆栈跟踪信息确定有关异常原因和发生位置的信息。

程序集加载跟踪: 下列信息有助于确定程序集“AjaxControlToolkit”无法加载的原因。

警告: 程序集绑定日志记录被关闭。
要启用程序集绑定失败日志记录，请将注册表值 [HKLM\Software\Microsoft\Fusion!EnableLog] (DWORD)设置为 1。
注意: 会有一些与程序集绑定失败日志记录关联的性能损失。
要关闭此功能，请移除注册表值 [HKLM\Software\Microsoft\Fusion!EnableLog]。

堆栈跟踪:

[FileLoadException: 未能加载文件或程序集“AjaxControlToolkit”或它的某一个依赖项。拒绝访问。]

[FileLoadException: 未能加载文件或程序集“AjaxControlToolkit, Version=1.0.10123.0, Culture=neutral, PublicKeyToken=28f01b0e84b6d53e”或它的某一个依赖项。拒绝访问。]
   System.Reflection.Assembly._nLoad(AssemblyName fileName, String codeBase, Evidence assemblySecurity, Assembly locationHint, StackCrawlMark& stackMark, Boolean throwOnFileNotFound, Boolean forIntrospection) +0
   System.Reflection.Assembly.nLoad(AssemblyName fileName, String codeBase, Evidence assemblySecurity, Assembly locationHint, StackCrawlMark& stackMark, Boolean throwOnFileNotFound, Boolean forIntrospection) +43
   System.Reflection.Assembly.InternalLoad(AssemblyName assemblyRef, Evidence assemblySecurity, StackCrawlMark& stackMark, Boolean forIntrospection) +127
   System.Reflection.Assembly.InternalLoad(String assemblyString, Evidence assemblySecurity, StackCrawlMark& stackMark, Boolean forIntrospection) +142
   System.Reflection.Assembly.Load(String assemblyString) +28
   System.Web.Configuration.CompilationSection.LoadAssemblyHelper(String assemblyName, Boolean starDirective) +46

[ConfigurationErrorsException: 未能加载文件或程序集“AjaxControlToolkit, Version=1.0.10123.0, Culture=neutral, PublicKeyToken=28f01b0e84b6d53e”或它的某一个依赖项。拒绝访问。]
   System.Web.Configuration.CompilationSection.LoadAssemblyHelper(String assemblyName, Boolean starDirective) +613
   System.Web.Configuration.CompilationSection.LoadAllAssembliesFromAppDomainBinDirectory() +203
   System.Web.Configuration.CompilationSection.LoadAssembly(AssemblyInfo ai) +105
   System.Web.Compilation.BuildManager.GetReferencedAssemblies(CompilationSection compConfig) +178
   System.Web.Compilation.BuildProvidersCompiler..ctor(VirtualPath configPath, Boolean supportLocalization, String outputAssemblyName) +54
   System.Web.Compilation.CodeDirectoryCompiler.GetCodeDirectoryAssembly(VirtualPath virtualDir, CodeDirectoryType dirType, String assemblyName, StringSet excludedSubdirectories, Boolean isDirectoryAllowed) +8812194
   System.Web.Compilation.BuildManager.CompileCodeDirectory(VirtualPath virtualDir, CodeDirectoryType dirType, String assemblyName, StringSet excludedSubdirectories) +128
   System.Web.Compilation.BuildManager.CompileCodeDirectories() +265
   System.Web.Compilation.BuildManager.EnsureTopLevelFilesCompiled() +320

[HttpException (0x80004005): 未能加载文件或程序集“AjaxControlToolkit, Version=1.0.10123.0, Culture=neutral, PublicKeyToken=28f01b0e84b6d53e”或它的某一个依赖项。拒绝访问。]
   System.Web.Compilation.BuildManager.ReportTopLevelCompilationException() +58
   System.Web.Compilation.BuildManager.EnsureTopLevelFilesCompiled() +512
   System.Web.Hosting.HostingEnvironment.Initialize(ApplicationManager appManager, IApplicationHost appHost, IConfigMapPathFactory configMapPathFactory, HostingEnvironmentParameters hostingParameters) +729

[HttpException (0x80004005): 未能加载文件或程序集“AjaxControlToolkit, Version=1.0.10123.0, Culture=neutral, PublicKeyToken=28f01b0e84b6d53e”或它的某一个依赖项。拒绝访问。]
   System.Web.HttpRuntime.FirstRequestInit(HttpContext context) +8893503
   System.Web.HttpRuntime.EnsureFirstRequestInit(HttpContext context) +85
   System.Web.HttpRuntime.ProcessRequestInternal(HttpWorkerRequest wr) +259