IE7以下:

My.Computer.Registry.SetValue("HKEY_CURRENT_USER\AppEvents\Schemes\Apps\Explorer\Navigating\.Current", "", "")

 

IE7:

 

代码
Private Const FEATURE_DISABLE_NAVIGATION_SOUNDS As Integer = 21
Private Const SET_FEATURE_ON_THREAD As Integer = &H1
Private Const SET_FEATURE_ON_PROCESS As Integer = &H2
Private Const SET_FEATURE_IN_REGISTRY As Integer = &H4
Private Const SET_FEATURE_ON_THREAD_LOCALMACHINE As Integer = &H8
Private Const SET_FEATURE_ON_THREAD_INTRANET As Integer = &H10
Private Const SET_FEATURE_ON_THREAD_TRUSTED As Integer = &H20
Private Const SET_FEATURE_ON_THREAD_INTERNET As Integer = &H40
Private Const SET_FEATURE_ON_THREAD_RESTRICTED As Integer = &H80

<SecurityCritical(), SuppressUnmanagedCodeSecurity(), DllImport("urlmon.dll", ExactSpelling:=True)> _
Public Shared Function CoInternetSetFeatureEnabled(ByVal featureEntry As Integer, ByVal dwFlags As Integer, ByVal fEnable As Boolean) As Integer
End Function




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CoInternetSetFeatureEnabled(FEATURE_DISABLE_NAVIGATION_SOUNDS, SET_FEATURE_ON_PROCESS, True)