Change the hightlight item color



<ListBox>
  <ListBox.Resources>
    <SolidColorBrush Color="Red" x:Key="{x:Static SystemColors.HighlightBrushKey}"/>
  </ListBox.Resources>
  <ListBoxItem Content="Item #1"/>
  <ListBoxItem Content="Item #2"/>
  <ListBoxItem Content="Item #3"/>
  <ListBoxItem Content="Item #4"/>
</ListBox>