Firstly, using space-borne remote sensing images, topographic maps and other relevant data, the surrounding sites of SKA in a 1000 km radius circle region centered in Guizhou Province has been searched and a lot of Karst depressions were found compatible for the construction of SKA. According to historical records, remote sensing images analysis and local engineering geological and hydrological survey, many aspects were studied and evaluated in order to select the optimal site.