1.打开Terminal
2.输入/System/Library/Frameworks/CoreServices.framework/Versions/A/Frameworks/LaunchServices.framework/Versions/A/Support/lsregister -kill -r -domain local -domain system -domain user
3.按下Enter
另外补充一个工具:
如果是要清理photoshop可以使用这个工具
http://helpx.adobe.com/creative-suite/kb/cs5-cleaner-tool-installation-problems.html