建立一个文件 register.py 内容如下. 然后执行该脚本. 

import sys

from winreg import *

# tweak as necessary
version = sys.version[:3]
installpath = sys.prefix

regpath = "SOFTWARE\\Python\\Pythoncore\\%s\\" % (version)
installkey = "InstallPath"
pythonkey = "PythonPath"
pythonpath = "%s;%s\\Lib\\;%s\\DLLs\\" % (
    installpath, installpath, installpath
)


def RegisterPy():
    try:
        reg = OpenKey(HKEY_CURRENT_USER, regpath)
    except EnvironmentError as e:
        try:
            reg = CreateKey(HKEY_CURRENT_USER, regpath)
            SetValue(reg, installkey, REG_SZ, installpath)
            SetValue(reg, pythonkey, REG_SZ, pythonpath)
            CloseKey(reg)
        except:
            print("*** Unable to register!")
            return
        print("--- Python", version, "is now registered!")
        return
    if (QueryValue(reg, installkey) == installpath and
                QueryValue(reg, pythonkey) == pythonpath):
        CloseKey(reg)
        print("=== Python", version, "is already registered!")
        return
    CloseKey(reg)
    print("*** Unable to register!")
    print("*** You probably have another Python installation!")


if __name__ == "__main__":
    RegisterPy()