必读综述列表
持续添加~
基因组学
2020 - NRG - The road ahead in genetics and genomics
2019 - NRG - RNA sequencing: the teenage years 【中文导读】
2021 - Nature - Closing in on a complete human genome 【中文翻译】
2020 - EME - Single-cell multiomics: technologies and data analysis methods【scMulti-omics】
2017 - GB - Multi-omics approaches to disease【Multi-omics】
2020 - BMC - A scoping review and proposed workflow for multi-omic rare disease research 【Multi-omics】
2021 - BIB - Multi-omics approaches for revealing the complexity of cardiovascular disease
2020 - BBI - Multi-omics Data Integration, Interpretation, and Its Application
遗传学
2019 - NRG - Genetic correlations of polygenic disease traits: from theory to practice【遗传相关性，当下研究热点】
2011 - NRG - The importance of phase information for human genomics【haplotype的重要性】
2020 - NRN - mGWAS: next generation genetic prediction in kidney disease
基因表达
2012 - Genetics - Gene Overexpression: Uses, Mechanisms, and Interpretation 【基因高表达也会导致defect，这种意识在分析基因表达数据时非常重要】
转录调控
转录因子
2018 - Cell - The Human Transcription Factors 【中文导读】
2011 - PB - A User's Guide to the Encyclopedia of DNA Elements (ENCODE)
2014 - NRG - Transcriptional enhancers: from properties to genome-wide predictions
2015 - EMM - CTCF as a multifunctional protein in genome regulation and gene expression【CTCF】
转录调控与疾病
Transcriptional Regulation and Its Misregulation in Disease - 2013 - Cell
单细胞表观遗传技术
The epigenetic basis of cellular heterogeneity - 2021 - NRG
增强子变异【更多相关：enhancer variant TF】
Enhancer variants: evaluating functions in common disease - 2014 - Genome Med
调控区域罕见变异
Deregulated Regulators: Disease-Causing cis Variants in Transcription Factor Genes - 2020 - Trends in Genetics
超级增强子
2020 - NPJ - Super-enhancer function and its application in cancer targeted therapy
单细胞应用综述
The single-cell sequencing: new developments and medical applications - 2019 - Cell & Bioscience
Progress and applications of single-cell sequencing techniques - 2020 - Infection, Genetics and Evolution
可变剪切
2013 - Nature - A compendium of RNA-binding motifs for decoding gene regulation【RNA binding motif】
表观调控
信号调控
2020 - NRG - Deciphering cell–cell interactions and communication from gene expression 【细胞互作】
2021 - NCB - Strategies for monitoring cell–cell interactions【细胞互作研究策略】
代谢通路
2001 - Cytokine Growth Factor Rev - The GDNF/RET signaling pathway and human diseases【HSCR TCA的特殊通路】
单细胞
2021 - NRG - Statistical mechanics meets single-cell biology
发育
2014 - CSC - Regulatory Principles of Pluripotency: From the Ground State Up 【从受精卵开始的自驱性的基因程序，吾毕生之所追寻】
特定疾病
2019 - Hirschsprung's Disease and Allied Disorders - Genetics of Hirschsprung’s Disease
其他
2018 - Front. Syst. Neurosci - Multiple Approaches to the Investigation of Cell Assembly in Memory Research—Present and Future【神经元环路组装】
一些想法
virtual cell
是什么在驱动，细胞和个体的，遗传、发育、衰老、死亡？
模拟解释自驱性的遗传发育病变衰老死亡，解决生老病死的问题。
