Top 13 Visual Studio Keyboard Shortcuts

1. F5: Start your project in debug mode
   
   
   
2. F7 & Shift-F7: Show the code windows & Show the designer window
   
   
   
3. Alt-Enter: Show the properties panel for a selected object (this is general Windows shortcut that can be used on files and directories)
   
   
   
4. F6 / Shift-F6 / Ctrl-Shift-B: Build solution / Build project / Build solution
   
    
   
5. Shift-Alt-C: Add a new class to your project
   
    
   
6. Ctrl-K + Ctrl-C: Comment a selected block of code
   
   
   
7. Ctrl-K + Ctrl-U: Un-comment a selected block of code
   
   
   
8. Ctrl-M + Ctrl-O / Ctrl-M + Ctrl-P: Collapse all code to definitions / Expand all code (stop collapsing)
   
   
   
9. Ctrl-M + Ctrl+M: Expend or collapse a selected code fragment. The code collapsed depends on where the cursor is located
   
   
   
10. Ctrl-B + Ctrl-T: Toggle code bookmark
    
    
    
11. Ctrl-Alt-P: Attach the debugger to a process. This is insanely useful for debugging ASP.NET web sites without having to start the project in debug mode
    
    
    
12. Ctrl-Alt-L: Show the solution explorer
    
     
    
13. Ctrl-Shift-A / Alt-Shift-A: Add a new item to your project / add an existing item to your project
    
    
    

The above list is my top 13. Did I miss any essential ones? What are yours?

Bonus:

The following work in Visual Studio just like they do in most other Windows application.

Ctrl-N: Add a new file

Ctrl-S: Save file

Ctrl-Z / Ctrl-Y: Undo typing / Redo typing

Ctrl-F: Bring up the "Find" dialog

Ctrl-H: Bring up the "Replace" dialog

Ctrl-Tab: Scroll forward through open windows

Ctrl-Shift-Tab: Scroll backwards through open windows