多个逗号，

update instantMessage set state = '8', networkPath = 'http://192.168.0.249/zcl/php/Public/uploads/20140126/52e4c1ecb4884.jpg' ,sNetworkPath = 'http://192.168.0.249/zcl/php/Public/uploads/20140126/200*150_52e4c1ecb4884.jpg'  ,  where messageId = '20140126160640'